Klow 80mg

Klow 80mg

$150.00
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Klow 80mg
  • Klow 80mg
  • Klow 80mg
  • Klow 80mg
  • Klow 80mg
Klow 80mg

Klow 80mg

$150.00

KLOV 80mg (GDF11): High-Potency Rejuvenation Research Peptide

KLOV, a research-grade formulation of GDF11 (Growth Differentiation Factor 11), is a member of the transforming growth factor-beta (TGF-$\beta$) superfamily. Often referred to in literature as a "rejuvenation factor," GDF11 is a circulating protein that declines with age. At the 80mg research concentration, it is primarily utilized in advanced studies focusing on systemic aging reversal, cardiac hypertrophy, and skeletal muscle regeneration.

Research Highlights

  • Systemic Rejuvenation: Extensively researched for its "pro-youthful" effects, particularly in parabiosis models where it has been shown to reverse age-related functional decline in multiple organs.

  • Cardiac Hypertrophy Reversal: Investigated for its ability to reduce the thickness of the heart wall in aging models, potentially restoring youthful cardiac function and elasticity.

  • Neurogenesis & Vascularity: Studies suggest GDF11 stimulates the growth of new neurons and improves cerebral blood flow, making it a critical subject for age-related cognitive decline research.

  • Skeletal Muscle Regeneration: Acts as a potent regulator of muscle stem cells (satellite cells), researched for its capacity to improve muscle repair and combat sarcopenia.

  • Genomic Stability: Emerging data focuses on its role in maintaining DNA integrity and regulating cellular senescence pathways.

Safety & Research Warning

  • RESEARCH USE ONLY: This material is strictly for laboratory research and in vitro testing. It is not for human or veterinary consumption.

  • Regulatory Status: KLOV (GDF11) is an experimental compound and is not FDA-approved for the treatment of any medical condition.

  • Handling: Due to the high concentration (80mg), extreme care must be taken during reconstitution to avoid aerosolization. Use full PPE.

Storage & Stability

  • Lyophilized Powder: Extremely stable when stored at -20°C to -80°C (up to 3 years). Avoid prolonged exposure to room temperature.

  • Reconstituted Solution: Must be stored at 2°C – 8°C. Unlike smaller peptides, GDF11 is a large protein and is highly susceptible to "sticking" to plastic; use of low-protein binding vials is recommended. Use within 7 days post-reconstitution.

  • Sensitivity: Highly sensitive to shear stress. DO NOT SHAKE. Gently swirl to dissolve. Multiple freeze-thaw cycles will result in immediate loss of biological activity.

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