{"product_id":"klow-80mg","title":"Klow 80mg","description":"\u003ch2 data-path-to-node=\"0\" class=\"\"\u003eKLOV 80mg (GDF11): High-Potency Rejuvenation Research Peptide\u003c\/h2\u003e\n\u003cp data-path-to-node=\"1\"\u003e\u003cb data-path-to-node=\"1\" data-index-in-node=\"0\" class=\"\"\u003eKLOV\u003c\/b\u003e\u003cspan class=\"\"\u003e,\u003c\/span\u003e\u003cspan class=\"\"\u003e a research-grade formulation of \u003c\/span\u003e\u003cb data-path-to-node=\"1\" data-index-in-node=\"38\" class=\"\"\u003eGDF11\u003c\/b\u003e\u003cspan class=\"\"\u003e (Growth Differentiation Factor 11),\u003c\/span\u003e\u003cspan class=\"\"\u003e is a member of the transforming growth factor-beta (TGF-\u003c\/span\u003e\u003cspan class=\"math-inline\" data-math=\"\\beta\" data-index-in-node=\"136\"\u003e$\\beta$\u003c\/span\u003e\u003cspan class=\"\"\u003e) superfamily.\u003c\/span\u003e\u003cspan class=\"\"\u003e Often referred to in literature as a \"rejuvenation factor,\u003c\/span\u003e\u003cspan class=\"\"\u003e\" GDF11 is a circulating protein that declines with age.\u003c\/span\u003e\u003cspan class=\"\"\u003e At the 80mg research concentration,\u003c\/span\u003e\u003cspan class=\"\"\u003e it is primarily utilized in advanced studies focusing on systemic aging reversal,\u003c\/span\u003e\u003cspan class=\"\"\u003e cardiac hypertrophy,\u003c\/span\u003e\u003cspan class=\"\"\u003e and skeletal muscle regeneration.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"2\" class=\"\"\u003eResearch Highlights\u003c\/h3\u003e\n\u003cul data-path-to-node=\"3\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,0,0\"\u003e\u003cb data-path-to-node=\"3,0,0\" data-index-in-node=\"0\" class=\"\"\u003eSystemic Rejuvenation:\u003c\/b\u003e\u003cspan class=\"\"\u003e Extensively researched for its \"pro-youthful\" effects,\u003c\/span\u003e\u003cspan class=\"\"\u003e particularly in parabiosis models where it has been shown to reverse age-related functional decline in multiple organs.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,1,0\"\u003e\u003cb data-path-to-node=\"3,1,0\" data-index-in-node=\"0\" class=\"\"\u003eCardiac Hypertrophy Reversal:\u003c\/b\u003e\u003cspan class=\"\"\u003e Investigated for its ability to reduce the thickness of the heart wall in aging models,\u003c\/span\u003e\u003cspan class=\"\"\u003e potentially restoring youthful cardiac function and elasticity.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,2,0\"\u003e\u003cb data-path-to-node=\"3,2,0\" data-index-in-node=\"0\" class=\"\"\u003eNeurogenesis \u0026amp; Vascularity:\u003c\/b\u003e\u003cspan class=\"\"\u003e Studies suggest GDF11 stimulates the growth of new neurons and improves cerebral blood flow,\u003c\/span\u003e\u003cspan class=\"\"\u003e making it a critical subject for age-related cognitive decline research.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,3,0\"\u003e\u003cb data-path-to-node=\"3,3,0\" data-index-in-node=\"0\" class=\"\"\u003eSkeletal Muscle Regeneration:\u003c\/b\u003e\u003cspan class=\"\"\u003e Acts as a potent regulator of muscle stem cells (satellite cells),\u003c\/span\u003e\u003cspan class=\"\"\u003e researched for its capacity to improve muscle repair and combat sarcopenia.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,4,0\"\u003e\u003cb data-path-to-node=\"3,4,0\" data-index-in-node=\"0\" class=\"\"\u003eGenomic Stability:\u003c\/b\u003e\u003cspan class=\"\"\u003e Emerging data focuses on its role in maintaining DNA integrity and regulating cellular senescence pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"8\"\u003eSafety \u0026amp; Research Warning\u003c\/h3\u003e\n\u003cul data-path-to-node=\"9\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,0,0\"\u003e\u003cb data-path-to-node=\"9,0,0\" data-index-in-node=\"0\"\u003eRESEARCH USE ONLY:\u003c\/b\u003e This material is strictly for laboratory research and \u003ci data-path-to-node=\"9,0,0\" data-index-in-node=\"73\"\u003ein vitro\u003c\/i\u003e testing. It is not for human or veterinary consumption.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,1,0\"\u003e\u003cb data-path-to-node=\"9,1,0\" data-index-in-node=\"0\"\u003eRegulatory Status:\u003c\/b\u003e KLOV (GDF11) is an experimental compound and is not FDA-approved for the treatment of any medical condition.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,2,0\"\u003e\u003cb data-path-to-node=\"9,2,0\" data-index-in-node=\"0\"\u003eHandling:\u003c\/b\u003e Due to the high concentration (80mg), extreme care must be taken during reconstitution to avoid aerosolization. Use full PPE.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"10\"\u003eStorage \u0026amp; Stability\u003c\/h3\u003e\n\u003cul data-path-to-node=\"11\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,0,0\"\u003e\u003cb data-path-to-node=\"11,0,0\" data-index-in-node=\"0\"\u003eLyophilized Powder:\u003c\/b\u003e Extremely stable when stored at \u003cb data-path-to-node=\"11,0,0\" data-index-in-node=\"52\"\u003e-20°C to -80°C\u003c\/b\u003e (up to 3 years). Avoid prolonged exposure to room temperature.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,1,0\"\u003e\u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"0\"\u003eReconstituted Solution:\u003c\/b\u003e Must be stored at \u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"42\"\u003e2°C – 8°C\u003c\/b\u003e. Unlike smaller peptides, GDF11 is a large protein and is highly susceptible to \"sticking\" to plastic; use of low-protein binding vials is recommended. Use within \u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"215\"\u003e7 days\u003c\/b\u003e post-reconstitution.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,2,0\"\u003e\u003cb data-path-to-node=\"11,2,0\" data-index-in-node=\"0\"\u003eSensitivity:\u003c\/b\u003e Highly sensitive to shear stress. \u003cb data-path-to-node=\"11,2,0\" data-index-in-node=\"47\"\u003eDO NOT SHAKE.\u003c\/b\u003e Gently swirl to dissolve. Multiple freeze-thaw cycles will result in immediate loss of biological activity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Helix Forge","offers":[{"title":"Default Title","offer_id":53153772470637,"sku":null,"price":150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0987\/4269\/8349\/files\/Klow80mg.jpg?v=1774320133","url":"https:\/\/helixforgelabs.com\/products\/klow-80mg","provider":"Helix Forge","version":"1.0","type":"link"}