Melanton 2 10mg

Melanotan II 10mg: High-Affinity Melanocortin Receptor Agonist

Melanotan II (MT-2) is a synthetic cyclic heptapeptide analog of the naturally occurring $\alpha$-melanocyte-stimulating hormone ($\alpha$-MSH). Engineered for superior stability and potency, MT-2 is a staple in dermatological and metabolic research due to its non-selective agonism of melanocortin receptors. By crossing the blood-brain barrier, it influences systemic physiological processes ranging from pigmentation to appetite regulation and sexual behavior.

Research Highlights

• Melanogenesis Induction: Acts as a potent agonist of the MC1R receptor, stimulating the production of eumelanin in melanocytes. It is the primary subject for research involving skin photoprotection and pigmentation pathways.

• Metabolic & Anorexigenic Effects: Investigated for its role in energy homeostasis through the activation of MC4R. Research suggests it may suppress appetite and influence lipid metabolism in animal models.

• Neurological Arousal: Like its derivative PT-141, MT-2 is studied for its ability to trigger central nervous system mediated arousal by modulating pathways in the hypothalamus.

• Cyclic Stability: The lactam bridge (cyclization) between Aspartic Acid and Lysine ensures high resistance to proteolytic degradation, providing a significantly longer half-life than endogenous $\alpha$-MSH.

• Photoprotective Research: Extensively utilized in studies aiming to reduce UV-induced DNA damage by increasing melanin density without the need for high-level UV exposure.

Safety & Research Warning

• RESEARCH USE ONLY: This material is strictly for laboratory research and in vitro testing. It is not for human or veterinary consumption.

• Regulatory Status: Melanotan II is not FDA-approved and is not intended for the treatment, cure, or prevention of any medical condition.

• Handling: Research must be conducted in a controlled environment. Use appropriate PPE, including gloves and masks, to prevent accidental exposure or cross-contamination.

Storage & Stability

• Lyophilized Powder: Stable at room temperature for up to 30 days. For long-term integrity, store at -20°C (up to 24 months).

• Reconstituted Solution: Once reconstituted with bacteriostatic water, store at 2°C – 8°C. For maximum potency and to avoid peptide degradation, use within 14 days.

• Sensitivity: Highly sensitive to light and physical agitation. Avoid vigorous shaking of the vial, as this can break the delicate peptide bonds and the cyclic structure.