Mots C 10mg

MOTS-c 10mg: Mitochondrial-Derived Peptide for Metabolic Research

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a unique, naturally occurring 16-amino acid peptide encoded by the mitochondrial genome rather than the nuclear genome. As a "mitokine," it acts as a critical signaling molecule that regulates metabolic homeostasis and cellular energy. In research settings, MOTS-c is a primary focus for studies involving longevity, exercise mimesis, and systemic insulin sensitivity.

Research Highlights

• Exercise Mimetic Properties: Extensively researched for its ability to mimic the metabolic effects of physical exercise by activating the AMPK (AMP-activated protein kinase) pathway.

• Metabolic Flexibility: Investigated for its role in enhancing glucose utilization and fatty acid oxidation, potentially reversing diet-induced insulin resistance in research models.

• Mitochondrial Proteostasis: Studies suggest MOTS-c promotes the expression of nuclear genes involved in metabolic stress responses, helping cells adapt to nutrient deprivation or oxidative stress.

• Longevity & Anti-Aging: Frequently utilized in longevity research due to its observed capacity to maintain physical function and metabolic health during the aging process.

• Targeted Osteogenic Support: Emerging research indicates MOTS-c may influence bone metabolism by promoting osteoblast differentiation and inhibiting osteoclast activity.

Safety & Research Warning

• RESEARCH USE ONLY: This material is strictly for laboratory research and in vitro testing. It is not for human or veterinary consumption.

• Regulatory Status: MOTS-c is an experimental compound and is not FDA-approved for the treatment of any medical condition.

• Handling: Research must be conducted in a controlled environment. Use appropriate PPE, including gloves and masks, to prevent accidental exposure.

Storage & Stability

• Lyophilized Powder: Stable at room temperature for up to 4 weeks. For long-term storage, keep at -20°C to maintain 99% purity for up to 24 months.

• Reconstituted Solution: After reconstitution with sterile water or bacteriostatic water, store at 2°C – 8°C. Due to the delicate nature of mitochondrial-derived peptides, use within 7–10 days for maximum experimental accuracy.

• Sensitivity: Highly sensitive to bacterial contamination and temperature fluctuations. Do not leave the reconstituted vial at room temperature for extended periods.