{"product_id":"nad-500mg","title":"NAD + 500mg","description":"\u003ch2 data-path-to-node=\"0\"\u003eNAD+ 500mg: Essential Cellular Coenzyme\u003c\/h2\u003e\n\u003cp data-path-to-node=\"1\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"1\"\u003eNicotinamide Adenine Dinucleotide (NAD+)\u003c\/b\u003e is a critical coenzyme found in every living cell. It serves as a fundamental component in energy metabolism and cellular signaling. In research models, NAD+ is central to the study of mitochondrial function, DNA repair, and the biological processes of aging.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"3\"\u003eResearch Highlights\u003c\/h3\u003e\n\u003cul data-path-to-node=\"8\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,0,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"4,0,0\"\u003eMitochondrial ATP Production:\u003c\/b\u003e Functions as a key electron carrier in the oxidative phosphorylation pathway, directly influencing the efficiency of cellular energy production.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,1,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"4,1,0\"\u003eSirtuin Activation:\u003c\/b\u003e Acts as an essential substrate for sirtuins (SIRT1-7), a family of \"longevity proteins\" that regulate gene expression, stress resistance, and metabolic homeostasis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,2,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"4,2,0\"\u003eDNA Repair Mechanism:\u003c\/b\u003e Serves as a necessary cofactor for PARP (Poly-ADP Ribose Polymerase) enzymes, which detect and repair damaged DNA strands.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,3,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"4,3,0\"\u003eCircadian Rhythm Regulation:\u003c\/b\u003e Studied for its role in modulating the body's internal clock by influencing the activity of CLOCK-BMAL1 transcriptional complexes.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,4,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"4,4,0\"\u003eRedox Balance:\u003c\/b\u003e Critical for maintaining the NAD+\/NADH ratio, which is a primary indicator of cellular redox state and overall metabolic health.\u003cbr\u003e\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"6\"\u003eMolecular Structure \u0026amp; Details\u003c\/h3\u003e\n\u003cp data-path-to-node=\"7\"\u003eUnlike peptides, NAD+ is a \u003cb data-index-in-node=\"27\" data-path-to-node=\"7\"\u003edinucleotide\u003c\/b\u003e. It does not have an amino acid sequence. It consists of two nucleotides joined through their phosphate groups: one with an adenine base and the other with nicotinamide.\u003c\/p\u003e\n\u003cul data-path-to-node=\"8\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,1,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"8,1,0\"\u003ePurity:\u003c\/b\u003e 99% Pure\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,2,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"8,2,0\"\u003eForm:\u003c\/b\u003e Lyophilized powder \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"13\"\u003eStorage \u0026amp; Stability\u003c\/h3\u003e\n\u003cul data-path-to-node=\"14\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"14,0,0\"\u003eLyophilized Powder:\u003c\/b\u003e Store at \u003cb data-index-in-node=\"29\" data-path-to-node=\"14,0,0\"\u003e-20°C\u003c\/b\u003e for long-term stability. For immediate use, refrigeration at \u003cb data-index-in-node=\"96\" data-path-to-node=\"14,0,0\"\u003e2°C – 8°C\u003c\/b\u003e is acceptable for up to 3 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"14,1,0\"\u003eReconstituted Solution:\u003c\/b\u003e NAD+ is highly sensitive to temperature and light once in liquid form. Store at \u003cb data-index-in-node=\"104\" data-path-to-node=\"14,1,0\"\u003e2°C – 8°C\u003c\/b\u003e and use within \u003cb data-index-in-node=\"129\" data-path-to-node=\"14,1,0\"\u003e24–48 hours\u003c\/b\u003e for maximum experimental accuracy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,2,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"14,2,0\"\u003eDegradation Note:\u003c\/b\u003e Exposure to light and moisture will cause rapid degradation into nicotinamide and ADP-ribose. Keep vials tightly sealed.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Helix Forge","offers":[{"title":"500mg","offer_id":53156358914413,"sku":null,"price":120.0,"currency_code":"USD","in_stock":true},{"title":"1000mg","offer_id":53156358947181,"sku":null,"price":200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0987\/4269\/8349\/files\/NAD_500mg_20682722-78f2-4c1d-ae54-3bde9428b27e.jpg?v=1774319983","url":"https:\/\/helixforgelabs.com\/products\/nad-500mg","provider":"Helix Forge","version":"1.0","type":"link"}