{"product_id":"pt-141-10mg","title":"Pt 141 10mg","description":"\u003ch2 data-path-to-node=\"0\" class=\"\"\u003ePT-141 10mg: Synthetic Melanocortin Agonist for Neurological Research\u003c\/h2\u003e\n\u003cp data-path-to-node=\"1\"\u003e\u003cb data-path-to-node=\"1\" data-index-in-node=\"0\" class=\"\"\u003ePT-141\u003c\/b\u003e\u003cspan class=\"\"\u003e,\u003c\/span\u003e\u003cspan class=\"\"\u003e also known as \u003c\/span\u003e\u003cb data-path-to-node=\"1\" data-index-in-node=\"22\" class=\"\"\u003eBremelanotide\u003c\/b\u003e\u003cspan class=\"\"\u003e,\u003c\/span\u003e\u003cspan class=\"\"\u003e is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (\u003c\/span\u003e\u003cspan class=\"math-inline\" data-math=\"\\alpha\" data-index-in-node=\"120\"\u003e$\\alpha$\u003c\/span\u003e\u003cspan class=\"\"\u003e-MSH).\u003c\/span\u003e\u003cspan class=\"\"\u003e Developed from the tanning peptide Melanotan II,\u003c\/span\u003e\u003cspan class=\"\"\u003e PT-141 is uniquely distinguished by its ability to modulate the central nervous system (CNS) to influence physiological responses.\u003c\/span\u003e\u003cspan class=\"\"\u003e Unlike traditional research compounds that target vascular pathways,\u003c\/span\u003e\u003cspan class=\"\"\u003e PT-141 acts as a non-selective agonist of melanocortin receptors,\u003c\/span\u003e\u003cspan class=\"\"\u003e primarily targeting the brain's arousal and motivational centers.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"2\" class=\"\"\u003eResearch Highlights\u003c\/h3\u003e\n\u003cul data-path-to-node=\"3\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,0,0\"\u003e\u003cb data-path-to-node=\"3,0,0\" data-index-in-node=\"0\" class=\"\"\u003eCentral Nervous System Mechanism:\u003c\/b\u003e\u003cspan class=\"\"\u003e Operates directly via the CNS by activating melanocortin receptors (primarily \u003c\/span\u003e\u003cb data-path-to-node=\"3,0,0\" data-index-in-node=\"112\" class=\"\"\u003eMC3R\u003c\/b\u003e\u003cspan class=\"\"\u003e and \u003c\/span\u003e\u003cb data-path-to-node=\"3,0,0\" data-index-in-node=\"121\" class=\"\"\u003eMC4R\u003c\/b\u003e\u003cspan class=\"\"\u003e) in the hypothalamus,\u003c\/span\u003e\u003cspan class=\"\"\u003e a key regulatory area for sexual behavior and motivation.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,1,0\"\u003e\u003cb data-path-to-node=\"3,1,0\" data-index-in-node=\"0\" class=\"\"\u003eNeurogenic Arousal Induction:\u003c\/b\u003e\u003cspan class=\"\"\u003e Extensively researched for its ability to bypass peripheral vascular mechanisms to trigger arousal signals,\u003c\/span\u003e\u003cspan class=\"\"\u003e making it a primary subject for studies on hypoactive sexual desire disorder (HSDD).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,2,0\"\u003e\u003cb data-path-to-node=\"3,2,0\" data-index-in-node=\"0\" class=\"\"\u003eDopaminergic Synergy:\u003c\/b\u003e\u003cspan class=\"\"\u003e Investigations suggest that PT-141 stimulation leads to the release of dopamine in the medial preoptic area,\u003c\/span\u003e\u003cspan class=\"\"\u003e enhancing the \"reward\" and \"appetitive\" aspects of behavioral responses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,3,0\"\u003e\u003cb data-path-to-node=\"3,3,0\" data-index-in-node=\"0\" class=\"\"\u003eIsomer Stability:\u003c\/b\u003e\u003cspan class=\"\"\u003e Utilizes a \u003c\/span\u003e\u003cb data-path-to-node=\"3,3,0\" data-index-in-node=\"29\" class=\"\"\u003eD-Phenylalanine\u003c\/b\u003e\u003cspan class=\"\"\u003e isomer in its core sequence,\u003c\/span\u003e\u003cspan class=\"\"\u003e which significantly increases its resistance to enzymatic breakdown and enhances its binding affinity compared to natural ligands.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,4,0\"\u003e\u003cb data-path-to-node=\"3,4,0\" data-index-in-node=\"0\" class=\"\"\u003eComparative Selectivity:\u003c\/b\u003e\u003cspan class=\"\"\u003e While derived from Melanotan II,\u003c\/span\u003e\u003cspan class=\"\"\u003e PT-141 is refined to minimize the melanogenic (tanning) effects while maximizing the neurological signaling pathways.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"8\"\u003eSafety \u0026amp; Research Warning\u003c\/h3\u003e\n\u003cul data-path-to-node=\"9\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,0,0\"\u003e\u003cb data-path-to-node=\"9,0,0\" data-index-in-node=\"0\"\u003eRESEARCH USE ONLY:\u003c\/b\u003e This material is strictly for laboratory research and \u003ci data-path-to-node=\"9,0,0\" data-index-in-node=\"73\"\u003ein vitro\u003c\/i\u003e testing. It is not for human or veterinary consumption.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,1,0\"\u003e\u003cb data-path-to-node=\"9,1,0\" data-index-in-node=\"0\"\u003eRegulatory Status:\u003c\/b\u003e MOTS-c is an experimental compound and is not FDA-approved for the treatment of any medical condition.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,2,0\"\u003e\u003cb data-path-to-node=\"9,2,0\" data-index-in-node=\"0\"\u003eHandling:\u003c\/b\u003e Research must be conducted in a controlled environment. Use appropriate PPE, including gloves and masks, to prevent accidental exposure.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"10\"\u003eStorage \u0026amp; Stability\u003c\/h3\u003e\n\u003cul data-path-to-node=\"11\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,0,0\"\u003e\u003cb data-path-to-node=\"11,0,0\" data-index-in-node=\"0\"\u003eLyophilized Powder:\u003c\/b\u003e Stable at room temperature for up to 4 weeks. For long-term storage, keep at \u003cb data-path-to-node=\"11,0,0\" data-index-in-node=\"97\"\u003e-20°C\u003c\/b\u003e to maintain 99% purity for up to 24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,1,0\"\u003e\u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"0\"\u003eReconstituted Solution:\u003c\/b\u003e After reconstitution with sterile water or bacteriostatic water, store at \u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"98\"\u003e2°C – 8°C\u003c\/b\u003e. Due to the delicate nature of mitochondrial-derived peptides, use within \u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"182\"\u003e7–10 days\u003c\/b\u003e for maximum experimental accuracy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,2,0\"\u003e\u003cb data-path-to-node=\"11,2,0\" data-index-in-node=\"0\"\u003eSensitivity:\u003c\/b\u003e Highly sensitive to bacterial contamination and temperature fluctuations. Do not leave the reconstituted vial at room temperature for extended periods.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Helix Forge","offers":[{"title":"Default Title","offer_id":53153773977965,"sku":null,"price":100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0987\/4269\/8349\/files\/Pt14110mg.jpg?v=1774320216","url":"https:\/\/helixforgelabs.com\/products\/pt-141-10mg","provider":"Helix Forge","version":"1.0","type":"link"}